📈 INTRADAY WATCHLIST – May 1, 2026

Published on: May 1, 2026

Pre-market trading is dominated by explosive moves in healthcare and biotechnology, with CUE surging over 122% on expansion news and LABT jumping 61% after positive antimicrobial data. Small-cap names across sectors are printing massive relative volume, signaling aggressive positioning ahead of the regular session open while major indices hold modestly positive.

Traders should focus on confirmed breakouts above pre-market highs in high-RVOL setups, with tight risk management as volatility spikes in low-float names.

1️⃣ $CUE (Cue Biopharma) | 🧬 Healthcare / Biotechnology

Current Status:

Price: $32.78 (+122.39%)
Float: 3.24M
Volume: 6.37M (380% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 08:45 ET

Trading Levels:

Intraday Range: $21.10–$34.43
Key Support: $24.97 (PM open), $21.10 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $35.50 | T2 $38.00 | T3 $42.00 | T4 $46.00 | T5 $50.00
Stop Loss: $28.50 (dynamic, max 5% risk)
Trailing Stop: 12% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #1, +122% Chg, High Vol PM
Volume: 6.37M shares, $208M dollar volume (380% RVOL)
Indicators: RSI 85, MACD strong bullish, OBV surging, above VWAP
Pattern: Massive gap up and continuation (1m/5m)
Catalyst: Cue Biopharma Announces Strategic Expansion and Executive Appointments — News scans / TrendVision, May 1, 2026

2️⃣ $LABT (Lakewood-Amedex Biotherapeutics) | 🧬 Healthcare / Biotechnology

Current Status:

Price: $4.29 (+61.28%)
Float: 7.50M
Volume: 22.99M (620% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 08:55 ET

Trading Levels:

Intraday Range: $2.63–$4.69
Key Support: $2.73 (PM open), $2.63 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $4.80 | T2 $5.50 | T3 $6.20 | T4 $7.00 | T5 $8.00
Stop Loss: $3.70 (dynamic, max 5% risk)
Trailing Stop: 15% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #2, +61% Chg, Highest Vol
Volume: 22.99M shares, $98M dollar volume (620% RVOL)
Indicators: RSI 78, MACD bullish crossover, OBV rising, above VWAP
Pattern: Strong gap up on news (pre-market)
Catalyst: Lakewood-Amedex Biotherapeutics Announces Positive Antimicrobial Resistance Data for Lead Candidate Targeting Infected Diabetic Foot Ulcers — TrendVision / News scans, May 1, 2026

3️⃣ $ESPR (Esperion Therapeutics) | 🧬 Healthcare / Pharmaceuticals

Current Status:

Price: $3.135 (+56.75%)
Float: 253.39M
Volume: 41.12M (290% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 09:00 ET

Trading Levels:

Intraday Range: $3.11–$3.20
Key Support: $3.15 (PM open), $3.11 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $3.40 | T2 $3.60 | T3 $3.90 | T4 $4.20 | T5 $4.50
Stop Loss: $2.95 (dynamic, max 5% risk)
Trailing Stop: 10% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #3, +57% Chg, High Vol
Volume: 41.12M shares, $129M dollar volume (290% RVOL)
Indicators: RSI 72, MACD bullish, OBV accumulating, above VWAP
Pattern: Gap and go continuation (pre-market)
Catalyst: High-volume pre-market surge in pharma sector on sector rotation — Data scans, May 1, 2026

4️⃣ $SOBR (SOBR Safe) | 🤖 Technology / Security Systems

Current Status:

Price: $0.8306 (+52.13%)
Float: 1.88M
Volume: 53.57M (2,850% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 08:40 ET

Trading Levels:

Intraday Range: $0.5737–$0.97
Key Support: $0.673 (PM open), $0.5737 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $1.05 | T2 $1.25 | T3 $1.50 | T4 $1.80 | T5 $2.20
Stop Loss: $0.72 (dynamic, max 5% risk)
Trailing Stop: 15% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #4, +52% Chg, Extreme Vol
Volume: 53.57M shares, $43M dollar volume (2,850% RVOL)
Indicators: RSI 88, MACD parabolic, OBV exploding, above VWAP
Pattern: Vertical gap up on whale accumulation (pre-market)
Catalyst: Large whale accumulation and momentum breakout in security tech — TrendVision Scanner, May 1, 2026

5️⃣ $AKAN (Akanda) | 🧬 Healthcare / Pharmaceuticals

Current Status:

Price: $62.28 (+27.21%)
Float: 0.53M
Volume: 1.30M (245% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 09:05 ET

Trading Levels:

Intraday Range: $59.28–$72.90
Key Support: $67.00 (PM open), $59.28 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $68.00 | T2 $75.00 | T3 $85.00 | T4 $95.00 | T5 $110.00
Stop Loss: $57.00 (dynamic, max 5% risk)
Trailing Stop: 12% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #5, +27% Chg, High Turnover
Volume: 1.30M shares, $86M dollar volume (245% RVOL)
Indicators: RSI 76, MACD bullish, OBV rising, above VWAP
Pattern: Gap up with consolidation (pre-market)
Catalyst: Sector momentum in specialty pharma with elevated pre-market volume — Data scans, May 1, 2026

6️⃣ $CERS (Cerus) | 🧬 Healthcare / Medical Devices

Current Status:

Price: $2.50 (+23.15%)
Float: 114.11M
Volume: 354.60K (180% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 09:00 ET

Trading Levels:

Intraday Range: $2.15–$2.54
Key Support: $2.15 (PM open), $2.15 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $2.70 | T2 $2.90 | T3 $3.15 | T4 $3.40 | T5 $3.70
Stop Loss: $2.25 (dynamic, max 5% risk)
Trailing Stop: 10% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #6, +23% Chg, Steady Vol
Volume: 354.60K shares, $0.86M dollar volume (180% RVOL)
Indicators: RSI 68, MACD positive, OBV flat to up, above VWAP
Pattern: Measured gap up (pre-market)
Catalyst: Pre-market strength in medical devices sector on volume — Data scans, May 1, 2026

7️⃣ $TWLO (Twilio) | ☁️ Technology / Software – Infrastructure

Current Status:

Price: $179.45 (+21.20%)
Float: 194.55M
Volume: 157.16K (140% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 09:00 ET

Trading Levels:

Intraday Range: $173.50–$184.00
Key Support: $174.22 (PM open), $173.50 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $185.00 | T2 $192.00 | T3 $200.00 | T4 $210.00 | T5 $225.00
Stop Loss: $172.00 (dynamic, max 4% risk)
Trailing Stop: 8% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #7, +21% Chg, Institutional Flow
Volume: 157.16K shares, $28M dollar volume (140% RVOL)
Indicators: RSI 65, MACD bullish, OBV steady, above VWAP
Pattern: Steady pre-market climb (pre-market)
Catalyst: Cloud infrastructure names seeing pre-market interest on sector rotation — Data scans, May 1, 2026

8️⃣ $TLIH (Ten-League International) | 🏗️ Industrials / Specialty Services

Current Status:

Price: $2.94 (+21.14%)
Float: 5.79M
Volume: 271.88K (220% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 08:50 ET

Trading Levels:

Intraday Range: $2.66–$3.85
Key Support: $2.66 (PM open), $2.66 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $3.20 | T2 $3.50 | T3 $3.90 | T4 $4.30 | T5 $4.80
Stop Loss: $2.60 (dynamic, max 5% risk)
Trailing Stop: 12% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #8, +21% Chg, Rising Vol
Volume: 271.88K shares, $0.86M dollar volume (220% RVOL)
Indicators: RSI 70, MACD positive, OBV climbing, above VWAP
Pattern: Breakout gap (pre-market)
Catalyst: Pre-market momentum in industrials with volume confirmation — Data scans, May 1, 2026

9️⃣ $TEAM (Atlassian) | 🤖 Technology / Software – Application

Current Status:

Price: $82.44 (+20.19%)
Float: 167.77M
Volume: 581.30K (160% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 09:00 ET

Trading Levels:

Intraday Range: $81.11–$86.60
Key Support: $85.68 (PM open), $81.11 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $85.00 | T2 $88.00 | T3 $92.00 | T4 $97.00 | T5 $105.00
Stop Loss: $78.00 (dynamic, max 5% risk)
Trailing Stop: 8% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #9, +20% Chg, Steady Flow
Volume: 581.30K shares, $49M dollar volume (160% RVOL)
Indicators: RSI 64, MACD bullish, OBV positive, above VWAP
Pattern: Controlled gap up (pre-market)
Catalyst: Software sector strength with pre-market institutional buying — Data scans, May 1, 2026

🔟 $FIVN (Five9) | 🤖 Technology / Software – Application

Current Status:

Price: $20.54 (+19.42%)
Float: 57.74M
Volume: 180.56K (210% RVOL)
Key Times: Pre-market high 09:13 ET, Support test 09:05 ET

Trading Levels:

Intraday Range: $19.60–$20.75
Key Support: $19.92 (PM open), $19.60 (PM low)

Entry Confirmation:

Require 2+ consecutive 1m/5m closes above the entry zone with reversal or volume surge.
Do NOT enter on first touch without confirmation.
Targets: T1 $21.50 | T2 $22.80 | T3 $24.50 | T4 $26.50 | T5 $29.00
Stop Loss: $19.20 (dynamic, max 5% risk)
Trailing Stop: 10% (scaled to volatility)

Technical Confirmation:

Scanner Hits: Pre-Market Gainers #11, +19% Chg, Volume Surge
Volume: 180.56K shares, $3.6M dollar volume (210% RVOL)
Indicators: RSI 67, MACD positive, OBV rising, above VWAP
Pattern: Gap and hold (pre-market)
Catalyst: Cloud contact center names attracting pre-market volume on tech rotation — Data scans, May 1, 2026

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